Study of marginals annotations on a canon law manuscript. (Grenoble, public Library, ms. 37), the Jean d'André's Apparatus super Clementinas. These annotations can be attributed to Louis Roux (student of canon law during the 14th century) and to François Du Puy (doctor of civil and canon law, officialis of the bishop of Grenoble at the end of the 15th century). Their intellectual methods are rather similar because of their university formation. Nevertheless, their readings vary in two respects. First, they focus upon different themes. Second, they use the same manuscript in different ways. Louis Roux's purpose is to assimilate the pontifical text (Clementines) and its gloss (the Apparatus). Then, he tries to compare the gloss of Jean d'André with those of other canonists. Louis Roux brings out the theme of the Church institutions. The purposes of François Du Puy are connected with his career and his pastoral engagement at the side of a reformer bishop. His professional point of view appears in the brief and synthetic form and nature of his marginal annotations. Two themes can be linked to his office : an interest in the bishop's duties, and a clarification of financial questions. Other aspects of his notes are more personal and may be connected to the private library he bequeathed to the GrandeChartreuse monastery – in 1500 he leaves the secular life for the Carthusian Desert : his attraction for the monastic life (in its concrete aspects) and his intellectual sensibility which puts him close to the Christian humanists.