In the globalization context, internationalization of OECD SMEs is growing in importance and taking more and more place in Switzerland. New opportunities open to SME entrepreneurs, together with the support of private and/or public agencies as evidenced by its newspaper titles: “Export et internationalization: les PME Suisse s’envolent!” (Rezonance , 2016) or “ Novertur aide les PME à s’internationaliser” (Mathez, 2013). This report explores what are the modes of Swiss SMEs internationalization and how they can find new business opportunities in distant emerging markets? What are the internationalization drivers and what kind of strategies make possible to overcome various types of obstacles and risks? In order to find answers to these interrogations, the first part of this report reviews theories and concepts dealing with SME economics and management, and in particular SME internationalization. The second part of this report provides an analysis of the various empirical findings derived from the Swiss International Entrepreneurship Surveys published in 2007, 2010 and 2013 and conducted by the School of Management-Fribourg together with Swiss Postfinance. This part is complemented by a selection of qualitative interviews with Swiss SME experts. In the first part of this research paper, we will reflect on the theoretical aspect of this broad subject, after that we are going to analyse the three different SIES surveys and its statistics mentioned above. In the last part, we will confront the answers found in the theoretical part and the analysis of the three surveys with the answers of the experts. The main results of this study are based mainly on the SIES reports and implemented by the theoretical analysis. Several findings have been established; some of them are, the entrepreneurship orientation and the international experience of decision makers confirmed as key success factor in the internationalization process. Then, the growing importance of born global companies as well as their international success and specific competitive advantage. Lastly, the rising importance of networks in the success of foreign expansion has been confirmed.