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Article

French

ID: <

10670/1.1nx444

>

Where these data come from
Prescription behaviour in pregnant women: example of dealing with a depressive condition

Abstract

- How to prescribe a pregnant woman? The optimal attitude makes a compromise between, on the one hand, the indication of treatment and, on the other hand, the significance of the risk that treatment poses to the foetus and the mother. Compliance with a few simple principles can help in this process: — The relative lack of knowledge in this field requires, above all, an attitude based on the precautionary principle. — The period (1st, 2th or 3th quarter) during which the foetus will be exposed to the treatment envisaged is a key element in the reflection. — Choice treatment is the one which, among the effective alternatives, has the best safety profile during pregnancy, depending on the human observations available. — The risk-benefit balance for the patient and the foetus may be reversed during pregnancy. — Any problematic medication exposure during pregnancy must be announced at one of the Swiss pharmacovigilance centres. These teratovigilance data are essential to inform knowledge in this field. — In order to illustrate these general principles, a typical example of prescription in pregnant women has been chosen, highlighting a newly identified problem of teratovigilance: the risks associated with certain antidepressants during pregnancy.

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