the main objective of this article is to reflect on the main interactions between theatre, science and technology, throughout the history of the theatre, and to discuss, from our experience in Science in Cena, an integral space of the Museum of Life, how these interactions can be present in the cotidian of a science museum. The word science should be understood here in a broad sense, encompassing not only natural sciences, but also humanities, as well as the word technology should be associated with applied science. Art and science will be understood as creative processes, as ways of representing the world and expressing human knowledge.