International audience The contribution covers the history of the Italian transmission of the Liber glossarum, from the oldest manuscript produced in the Milan area, the Ambrosiano B 36 inf. dating back to the IX century, to the Vat. Lat. 1461-1462 written and decorated in Tuscany, and later acquired by Pope Sixtus IV in 1477. The manuscripts and the fragments studied are placed in connection with the two textual families of the encyclopedia, φ and γ, and some information is considered on the indirect tradition, particularly on the excerpta used by Domenico di Bandino, Coluccio Salutati and Sozomeno da Pistoia.