This article is intended to be an exploration of the topic of self-knowledge among stoicy philosophers Epictet and Marc-Aurèle. In the light of the socratic definition of gnothi seauton (know yourself), we propose to look at the ‘philosophy of self-esteem’ that Épictet and Marc-Aurèle have developed. More specifically, we would like to explain the famous distinction made by Epictet in his Manual (which will be taken up by Marc-Aurèle in his Things for myself) between what depends on us (judgements, trends, desires, aversions, etc.) and what does not depend on us (body, celebrity, wealth, power). From the stoicy perspective of Epictet and Marc-Aurèle, we will seek to demonstrate that “knowing oneself” means being able to identify what depends on our jurisdiction, and therefore not subject to the Destin.