This communication is based on some of the results of the METAL project (Latin American Metropoles in Globalisation: territorial reconfigurations, space mobility, public action, led by F. Dureau), financed under the ANR/aird programme “Les Suds hui”. This research, involving an international and multidisciplinary team of 25 researchers, covers three Latin American metropolitan areas, Bogotá, Santiago du Chile and São Paulo. The aim is to study the socio-spatial reconfigurations that have been taking place in Latin American metropolitan areas since the 1980s, in particular the evolution of population and new forms of social differentiation within the urban space. In order to carry out this study, two usually separate entries are combined: the behaviour of residents (urban practices and mobility systems, from international traffic to daily travel) and the various registers of public action (migration policy, urban planning, action on housing or transport). It is a question of understanding how the combination of these two factors contributes to transforming the Latin American metropolitan model inherited from the 1980s. The comparative approach is based on a methodology common to the three cities. In each of these, a metropolitan analysis is articulated with case studies on illustrative neighbourhoods of current mutations. Empirical work is based on the exploitation of censor micro-data and the production of new data on mobility, using an original survey methodology. The combination of methods of demography (biographical approach) and geography (GIS, spatial analysis) makes it possible to analyse both individual and local dynamics at the same time. This communication will be limited to the example of Bogotá, a city studied more specifically by the authors of the communication. It will focus on the general methodology of the survey and the initial results observed in an area chosen for its emblematic nature of the evolution of accessibilities in the Colombian capital: the Calle 80 sector, marked by a radical change in transport supply with the introduction of the first line of the Transmilenio in 2001, and the associated urban changes in the provision of housing and services. On the basis of this example, on the one hand, the aim will be to contribute to the discussion of methods for observing mobility practices and, on the other hand, to suggest some avenues for reflection on the analysis of inequalities in access to urban resources in a global and biographical approach to mobility. In particular, the question arises as to how the inhabitants of this changing Bogota sector are mobilising new transport, housing and service opportunities.