Porous graphene materials possess a unique structure with interconnected networks, high surface area, and high pore volume. Because of the combination of its remarkable architecture and intrinsic properties, such as high mechanical strength, excellent electrical conductivity, and good thermal stability, porous graphene has attracted tremendous attention in many fields, such as nanocomposites, lithium batteries, supercapacitors, and dye-sensitized solar cells. This chapter reviews synthesis methods, properties, and several key applications of porous graphene materials.