This article provides Russian and foreign experience of successful implementation of projects for redevelopment of industrial zones in large cities. Some projects implemented in Moscow, St. Petersburg are considered in more details. Among foreign projects, the experience of such countries as Great Britain, the USA and China (Hong Kong) should be especially noted. The main goal of the redevelopment of industrial zones in large cities in Russia is to maintain a balance between comfort and convenience for citizens and the interest of investors to give in the implementation of such investment projects. The implementation of projects in the Russian Federation started in 2010. At present, part of the industrial zones in Moscow and St. Petersburg has been almost completely reorganized. Residential complexes, social and cultural facilities, shopping and entertainment centers, roads, parking lots and other infrastructure facilities have been built today instead of industrial zones. In order to meets the requirements of the modern economy, in some cases, industry production has been preserved. The main problems in the implementation of redevelopment projects have been identified, among them are: the absence of the necessary legislation and a clear systemic plan for the reorganization of urban spaces. The authors of the article propose to create a clear concept in Russia for the transformation and redevelopment of industrial areas based on the integrated development of entire residential neighborhoods with all infrastructure facilities, which must be adopted and evaluated with the support of government authorities.