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Effect of probiotics on the prevention and treatment of cancer and Diabetes mellitus

Articles

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Abstract

Diet rich in probiotics helps in the prevention and treatment of diseases, as well as in the balance of the intestinal microbiota. This is a literature review that sought to assess the effect of probiotics on the prevention and treatment of cancer and diabetes. The electronic databases were: Scielo, LILACS, Virtual Health Library, Google Scholar, Medline and Pubmed, articles in English, Spanish and Portuguese, descriptors: Probiotics / Probiotics, Probiotics and diabetes / Probiotics and diabetes and Probiotics and cancer / Probiotics and cancer; Inclusion criteria: full articles published in full, available in English, Spanish and Portuguese, in the last 20 years. Initially found 12,000 articles with the descriptor probiotics, other descriptors, the final result of 210 articles was obtained. It was observed that cancer and diabetes are chronic diseases, considered by the World Health Organization (WHO) as priority problems of global public health, studies have shown beneficial actions with the use of probiotics with in vivo and in vitro research in cancer , probiotics reduce mutagenic and genotoxic effects, act with three host protection mechanisms, in diabetes, probiotics can improve metabolic changes such as insulin resistance, hyperglycemia, inflammation, dyslipidemia or NAFLD in animals and act with beneficial mechanisms. The use of probiotics has a beneficial role in the treatment of chronic non-communicable diseases such as cancer and diabetes. In cancer, probiotic bacteria reduce mutagenic and genotoxic effects, the benefits of probiotics in diabetes mellitus are the improvement in metabolic changes associated with diabetes, such as insulin resistance, hyperglycemia and inflammation.

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