Remotely sensed geophysical datasets are being produced at increasingly fast rates to monitor various aspects of the Earth system in a rapidly changing world. The efficient and innovative use of these datasets to understand hydrological processes in various climatic and vegetation regimes under anthropogenic impacts has become an important challenge, but with a wide range of research opportunities. The ten contributions in this Special Issue have addressed the following four research topics: (1) Evapotranspiration estimation; (2) rainfall monitoring and prediction; (3) flood simulations and predictions; and (4) monitoring of ecohydrological processes using remote sensing techniques. Moreover, the authors have provided broader discussions on how to capitalize on state-of-the-art remote sensing techniques to improve hydrological model simulations and predictions, to enhance their skills in reproducing processes for the fast-changing world.