[EN] Adversity as misfortune has been a part of the inevitable existence of the human being, who, in experimenting such misfortune in their own flesh, has become aware of the world around them. These experiences, which always imply a learning process, sometimes also involve an individual’s bodily metamorphosis. An information and/or deformation which conditions life and thought. To us, furthermore, this becomes a nucleus for reflection, analysis, and transmission of knowledge. Likewise, as creatives, this allows us to develop our craft as a means of introspection, meditation, and appropriation of our experience. Adverse experiences such as pain, death, illness, suffering, and their impact on time have been a reason for reflection and creative fuel for contemporary artists within the national and international panorama. In this article, which is developed within our line of research concerning art and illness, we will focus on an analysis of the works of Rossana Zaera and Teresa Cebrián. These two artists, who, in dealing themes of transcultural character for the individual, have channeled their own experience of reality which surrounds them through artistic creation. Their reflection and investigation have allowed them to delve into the dark reality which torments the human being and to transmit their concerns through the width of possibilities their artistic representation grants.