[EN] This work has been developed in Pharmacology and Pharmacotherapy subject of the third year of the Degree in Veterinary Medicine at the University of Zaragoza. Problem-Based Learning (PBL) with simulated cases has been used, providing a relatively large period of decision-making. This experience has been raised using a model of animal research for teaching of Pharmacology. Students, in groups, must put appropriate treatment in each of the phases of the implementation of the model (from the initial anesthesia to antibiotic treatment and final resolution process). In addition to applying the knowledge acquired in the subject, with teacher support in all cases, the student has had to make reasoned decisions about the problems that have arisen in real time. In assessing students it has taken into account the report of the actions motivated and rigor at work and teamwork. Finally, it has conducted a survey to students to know their degree of satisfaction with the experience gained.