In this work we attempt to analyze the intra-theoretic characterization provided by Hilary Putnam and Werner Heisenberg between quantum mechanics and other theories. The first defended the idea that physical theories include macro principles that under specific definite historical conditions can be revised on the light of rival principles. Putnam will concentrate in the impact that quantum mechanics has produced in the classical image of knowledge. Heisenberg, on the other hand, develops his analysis from the notion of closed theories, assuming the independence and incommensurability of physical theories. These divergences between the two authors will allow us to analyze how the disagreement in the consideration of the status of physical theories, goes deeper into more profound aspects related to the nature of knowledge and the relation between theory and world.