The literature included sensory processing abnormalities (associated pain) in the diagnostic criteria for people with autism (ASD). However, we do not have any standardised method for assessing sensory abnormalities and pain behaviour in people with ASD. 46 adults with ASD were included in this study. Sensitivity to procedural and acute pain was assessed objectively in various contexts. We then analysed the correlation matrix and conducted a dimensional analysis. The correlation between pain sensitivity and clinical variables was significant. Co-morbidity was the main mediating factor between severity of autism and pain intensity. Our results suggest that our methodology can be used to assess pain sensitivity in adults with ASD and we confirm the assumption that co-morbidity is the main mediating factor between severity of autism and pain intensity.