This article outlines the substance of Latin American Indigenous Constitutionalism; as a manifestation of age-old cognitive practices, social demonstrations and emancipatory uprisings that validate the collective epistemological construction of the leadership of the state, society and life: this is its recognition rule. One objective is to concur as this constitutionalism irradiates a political approach that discourages the legionaries of deciduous constitutionalism, transnational constitutional theories and Mercatoria Lex; and, secondly, to ensure the ineffectiveness of the so-called New Constitutionalism implemented under the guidelines of the Trilateral Commission Report of 1975. The background describes three key conditions of the Latin American socio-economic and political crisis of the 1960s and 1970s and decisive for the establishment of the military dictatorships which, after bringing society home, organise the return to electoral democracy and the adoption of this new constitutionalism. The descriptive-analytical perspective assumed makes it possible to highlight the ethical change that contributes to the re-establishment of ‘other knowledge’, of ‘other powers’ in the context of the current political conflict, as well as its impact on the construction of a new hegemony for the power dispute. The record is that without being able to change there is no change.