This research aimed to find the best-operating conditions for incorporating the GO material into PES/GO membranes for the NF applications. Organic dye molecules may foul GO-NP/PES membranes. The improved model aimed to reduce the energy lost while maintaining a high system discharge throughout the treatment process in order to face the technical problems that the membranes are exposed to. To create a particular amount of flux above the intended values, an optimization approach was used to find the optimal values for several important parameters in the process. To enhance the process effectiveness on a broader scale, mathematical and statistical studies, such as response surface methodology and statistical analysis of the parameters (ANOVA), were applied. The impact of operational factors, like the pH values of the dye feeding (3 – 11), GO weight content (0 – 2 wt. %), dye concentration (10 – 100 ppm) of AB-210, and the interfaces for these factors with the PES/GO membrane permeability was examined. The PES membrane had the best performance, with a result of 131.2338 (L.m-2.h-1.bar-1). The pH did not influence the AB-210 dye reaction, and the Pareto chart of the standardized effects on dye permeation flux using statistical comparison at the 5% significance level supports these findings.