Introduction. Intimate partner violence (VP) is a complex phenomenon composed of multiple micro- and macro structural and priority factors for public health. The aim of the study was to identify interventions to prevent VP targeting the Latin and Hispanoamerican population through a systematic review based on the guidelines of the Joanna Briggs Institute. Methodology. Studies were extracted from PubMed, EBSCO, PsycINFO, Web of Sciences, Scopus and Scielo through a specific search strategy for each database. Anti-VP articles were included in Latin or Spanish-American populations between 13 and 24 years old, published in English or Spanish and until July 2020. After the removal of duplicates, 1031 titles and summaries were reviewed, 31 were revised in full text in pairs, and six were included in the synthesis of the evidence. Results. Four studies showed medium quality and two high quality according to Joanna Briggs Institute guidelines. Four were conducted in EUA and two in Mexico. Of the characteristics of the total samples of interventions, the age range was 13 to 23 years, all targeting both sexes. Interventions took place in educational institutions. The shortest intervention was a four-hour session and the largest one of 18 sessions. Five of the interventions were based on theory, such as the Social Learning Theory, Cognitive Social Theory, Opmido Theatre, Social Development Model. One of them used at the same time participatory community methodology. Significant results were reduced acceptance of violence, increased self-efficiency in resolving non-violent conflicts and increased intentions not to act violently, increased perceptions and attitudes towards violence, increased awareness of violence, less acceptance of women’s aggression over men and increased search for help. Discussion and conclusions. There are few VP prevention interventions in adolescents, young adults (adults) and culturally ad hoc in Latin and Spanish-American populations, when compared with available interventions that do not consider specific race or socio-cultural background criteria. The short duration of interventions remains an observable feature relative to the expected outcome for dependent variables, as this depends on behavioural change. Interventions to prevent VP can be promising when implemented in the educational context, including students, teaching and administrative staff, with participatory community approaches, considering the specificities of the socio-cultural and structural context that shapes violence against women. Adapting such interventions to similar contexts through systematic processes contributes to the transfer of knowledge and the improvement of innovations.