Barranquilla, a town located in an intertropical geographical latitude on the left bank of the mouth of the River Magdalena, is a bundle of pieces due to its urbanisation processes. Processes that start accelerated urban development in the early decades of the 20th century, without having a town planning plan for its vast area. In the absence of this, Burguese neighbourhoods are drawn up to accommodate European migration, and secondly, as a result of this development, the informal neighbourhoods established as a result of local and regional migration appear spontaneously. Among the Burmese neighbourhoods, a distinction is made between the El Prado Barrio, developed on the basis of the urban principles of the Modern Movement, following the model of Ciudad Jardín, thus constituting the main urban milestone of the city in the 20th century. This is how the Prado was characterised by the continuity of its route and by erecting on each of its land, architectural styles comparable to those built in North American and English cities of the time. These buildings currently include the construction of 54 isolated houses for the Barranquilla elite, the El Prado Hotel and the launch of the Country Club. The passage of time has led to functional transformations in the El Prado district which changed its symbols and imaginations. However, its declaration as a National Bien of Cultural Interest, through Resolution 0087 on 2 February 2005, has prevented the structural modification of its heritage architectural parts, roofs, courtyards and most of the plant species, as well as the urban route. At present, there is a confluence of integrated and complementary events in the neighbourhood, starting from those of residential use in the Caribbean, combined with the development of cultural activities in the public space, which are linked to cultural and artistic scenarios that have been established in the neighbourhood over time. This confluence has created a synergy between the model of the City of Jardín, the Caribbean’s residential everyday life, which is part of the architectural heritage, the culture hosted in heritage buildings and its extensive public spaces, reaffirming the living condition to be considered from a future issue. An understanding that also highlights unrecognised human manifestations, as the territory acquires other potential. This is how the Vivo El Prado Museum initiative boosts this value as a process of urban regeneration. The potential value of living, structured under the concept of Museum, through the urban regeneration process, includes the El Prado neighbourhood as a territory of key opportunities in cultural and innovation management, through the launch of other economic models, which exclude the possibility of gentrification. This research is thus embedded in a deepening of urban regeneration studies, understanding the image of the city as a work of art and research into the significance of museum in different instances. Giving concrete expression to the Vivo Museum’s concept as the definition of urban space which, in the first instance, does not draw its collection from the context, but, on the contrary, generates the collection around it, building on the space, culture, dynamic, symbiotic, socially balanced system, in which democratic and spontaneous dynamics develop and underpin a system of economic, natural and cultural balances. It is not a question of creating an inert environment, but of enabling actions and relationships between visitors and inhabitants that enhance these dynamics. This is how the Museo Vivo El Prado, proposed as a district of cultural and creative innovation, will not only generate economic impact and remuneration, but will enable the transformation of collective imaginaries, substantiating their identities and consolidating their image. This will be encouraged by its initial urban planning and dynamised by the ways in which they live in this heritage environment, and can be recognised as an ‘own brand’, from territorial marketing in terms of recognition and promotion within the city, based on the promotion of the orange economy, which is one of the Colombian National Government’s goals. In this way, the Vivo El Prado Museum is conceived on the basis of understanding heritage as a matter of future, separating itself from the traditional conception of a museum, i.e. a static, inert, inanimated, drawing the collection from its context and using the buildings as media for other arts. On the contrary, the Vivo El Prado Museum has the concept of a museum in the dimension of urban management and regeneration combined with creative economy processes, to be delivered to a democratic, public, open and open-air space. Urban space is the museum itself, its boundaries, the territory on which the administratively defined heritage lies and the sky as its upper corner.