El This article seeks to study the main legal challenges faced by the process of implementing the rules on the labelling and packaging of tobacco products in Colombia. For this info n, it is necessary to know the processes for drafting the legislation on tobacco control, the progress that the jurisprudence of the Colombian Constitutional Court has advanced on the issue and the administrative measures carried out by the Ministry of Health, a focal point on tobacco control in the country. It is also essential to recognise the relationship between that provision and its study, based on the MPOWER plan of measures, in particular with the measure prohibiting all forms of advertising, promotion and sponsorship of tobacco products. This has made it possible, on the basis of the harmonisation of the content of international legislation with Colombian domestic law, to structure the government’s policy guidelines and to implement the current legislation in full.