Query : Α7 nicotinic receptors
- Hollmann, Michael1
- Koukouli, Fani1
- Kudryavtsev, Denis1
- Maskos, Uwe1
- Methfessel, Christoph1
- Ojomoko, Lucy1
- Plantard, L.1
- Shelukhina, Irina1
- Spirova, Ekaterina1
- Tsetlin, Victor1
- Vetel, Steven1
- Werner, Markus1
- Biological Anthropology2
Neuroinflammation and neuroprotection in Parkinson's disease animal model mimicking the early stages of the disease (6-hydroxydopamine lesion in rat)
Currently, therapeutic strategies in Parkinson’s disease are symptomatic and the progression of the disease is uncontrolled, requiring the development of new neuroprotective approaches. Neuroinflammation plays a major role in the neurodegenerative process where it occurs early through the activation...
Molecular and cellular analysis of genodermatoses
Summary Skin is the essential interface between our body and its environment; not only does it prevent water loss and protect us from external insults it also plays an essential role in the central nervous system acting as a major sense organ primarily for touch and pain. The main cell type present...
The multiple roles of the α7 nicotinic acetylcholine receptor in modulating glutamatergic systems in the normal and diseased nervous system.
International audience Neuronal nicotinic acetylcholine receptors (nAChRs) play an important role in a variety of modulatory and regulatory processes including neurotransmitter release and synaptic transmission in various brain regions of the central nervous system (CNS). Glutamate is the principal...
Data from: Calcium imaging with genetically encoded sensor Case12: facile analysis of α7/α9 nAChR mutants
Elucidation of the structural basis of pharmacological differences for highly homologous α7 and α9 nicotinic acetylcholine receptors (nAChRs) may shed light on their involvement in different physiological functions and diseases. Combination of site-directed mutagenesis and electrophysiology is a pow...