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International audience The management of endangered species is complicated in the marine environment owing to difficulties to directly access, track and monitor in situ. Population genetics provide a genuine alternative to estimate population size and inbreeding using non-lethal procedures. The long...

International audience The distribution of genetic variation and the phylogenetic relationships between 18 populations of the arctic-alpine plant Trollius europaeus were analysed in three main regions (Alps, Pyrenees and Fennoscandia) by using dominant AFLP markers. Analysis of molecular variance re...

Expression of human leucocyte antigen (HLA) Class I molecules is essential for the recognition of malignant melanoma (MM) cells by CD8(+) T lymphocytes. A complete or partial loss of HLA Class I molecules is a potent strategy for MM cells to escape from immunosurveillance. In 2 out of 55 melanoma ce...

The cucumber (Cucumis sativus L.) is an important crop worldwide. In the present study, the molecular genetic diversity of 131 Spanish accessions was analyzed using 23 simple sequence repeat (SSRs). Eighteen of these SSRs were polymorphic; the mean number of alleles, mean observed heterozygosity and...

the short arm of chromosome 17 (17p) is frequently altered in human cancers, particularly in the p53 gene. However, in some cancers, changes in 17p occur in distal regions of p53, in the absence of any mutation in this gene. Analyses for the loss of heterozygoty and methylation of CpG islands in gen...

This study describes the intraspecific variation of 30 edible-seed Lagenaria siceraria germplasm accessions from the University of Abobo-Adjamé. These accessions were collected from three (Centre, East and South) geographical zones of Côte d’Ivoire. Selection based on seed size by the farmers has re...

The main objective of this study was to assess genetic comparison of two migratory forms of Caspian trout Salmo trutta caspius namely fall-run and spring-run. Owing to the lack of information on its genetic differences, 5 microsatellite loci were used for 58 sample analyses. Genomic DNA was extrac...

<p class="Default">Genetic identification among different 15 male genotypes of <em>Pistacia vera </em>L. species in comparison with five main commercial male cultivars accredited by Ministry of Agriculture (Adam, Jamil, Ebrahim, Elyas and Khalifa) was achieved using SSR markers. Seventeen primer pai...

Abstract This case presents a classic example of an African American individual who is heterozygous for sickle cell disease and who does not manifest any symptoms until he encounters extreme physical conditions. The case explores the initial presentation of sickle cell symptoms in a heterozygote, th...

Argali sheep is an ungulate, which inhabits the north, west, south and central regions of Mongolia. There are two major populations (Altai and Gobi) in Mongolia, but their taxonomic classification as subspecies is often disputed among researchers. Furthermore, there is no recent study about the popu...

Common kilka Clupeonella cultriventris (Nordmann, 1840) is a brackish water and small pelagic fish species and is one of the most abundant fishes that live gregariously in the Caspian Sea. A total of 60 specimens of adult common kilka were sampled from two seasons. Fifteen pairs of microsatellites...

The use of genetic diversity as a basis for identifying combinations which are superior to the parents, with a greater heterozygosity, is important in view of the difficulty when selecting promising genotypes for a breeding program. Given the above, the aim of this work was to evaluate genetic diver...

Genome-wide assessments of the genetic landscape of Farm Animal Genetic Resources (FAnGR) are key to developing sustainable breed improvements. Understanding the FAnGR adaptation to different environments and supporting their conservation programs from community initiative to national policymakers i...

Assessment of the diversity of reproductive traits and genetic variation is of great relevance to the conservation of genetic resources and management of silver fir (<i>Abies alba</i>) populations. We have evaluated reproductive characteristics associated with female cones and seed morphology, as we...

Italian maize germplasm is particularly rich in local materials and each region is characterized by the presence of peculiar local varieties deriving from centuries of adaptation, selection and cultivation. While the introduction of hybrids, during the 1950s, led to the disappearing of many of these...

The interaction of killer cell immunoglobulin-like receptors with their human leucocyte antigen ligands drives the activation and inhibition of natural killer cells. Natural killer cells could be implicated in the development of liver fibrosis in chronic hepatitis C. We analysed 206 non-transplanted...

Degree: Master of Science Abstract: Two concerns regarding the collection of data for brain and other central nervous system (CNS) tumours in Canada are under-reporting of non-malignant tumours and the need for improved reporting of clinically relevant molecular information. The first part of our st...

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We report the results of a cross-species amplification test of 156 bovine, ovine and cervid microsatellite markers in a wild population of mountain goats, Oreamnos americanus, inhabiting Caw Ridge, Alberta, Canada. Twenty-nine markers were found to be low to moderately polymorphic with between two t...

International audience We report the isolation, development and multiplex optimisation of 12 new microsatellite loci for the great scallop, Pecten maximus. Diversity was moderate to high, with number of alleles ranging from 4 to 20 and observed heterozygosity between 0.28 and 0.88. Progeny produced...

Mercurialis annua is a wind-pollinated annual plant that has long been used as a model for the study of ploidy and sexual-systems evolution. However, no molecular markers are yet available for genetic studies of its diploid populations. Here, we develop and characterize a set of eight polymorphic mi...

We calculated the linkage disequilibrium between all pairs of variants in the Drosophila Genome Reference Panel with minor allele count ≥5. We used r2 ≥ 0.5 as the cutoff for a highly correlated SNP. We make available the list of all highly correlated SNPs for use in association studies. Seventy-six...

The principal aims of this study were to explore genetic diversity and genome-wide selection signatures in Persian Arabian horses and to determine genetic relationship of Persian Arabians with other Iranian horse breeds. We evaluated 71 horses from 8 matrilineal strains tracing to 47 mares from the...

Many molecular ecology analyses assume the genotyped individuals are sampled at random from a population and thus are representative of the population. Realistically, however, a sample may contain excessive close relatives (ECR) because, for example, localized juveniles are drawn from fecund species...