Currently, therapeutic strategies in Parkinson’s disease are symptomatic and the progression of the disease is uncontrolled, requiring the development of new neuroprotective approaches. Neuroinflammation plays a major role in the neurodegenerative process where it occurs early through the activation...

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The analysis of some behavioral issues which affect communication in people with Parkinson’s Disease (PD) relative to their environment is performed in order to develop a proposal of communication based on relational anthropology. A bibliographical review was developed, along with a theoretical prop...

the main characteristics of parkinsonian speech are a sound disorder and prosodium destructuring. A review of the literature reveals contradictory results on changes in voice height related to Parkinson’s disease (CDM): increase, decrease or no difference of F0 compared to a control population. We p...

Melatonin in Parkinson’s Disease

The prevalence of neurodegenerative disorders is increasing dramatically and one of the major challenges today is the need of early and accurate diagnosis, the other is the need of more effective therapies -in turn the development of such therapies also requires early and accurate diagnosis-. The ma...

Degree: Doctor of Philosophy Abstract: Intrinsically disordered proteins (IDPs) represent a large subpopulation of the proteome, and are characterized by high structural plasticity and a predisposition to aggregate. These aggregates can accumulate inside or outside the cell, often forming amyloid pl...

This proposal aims to involve young students in upper secondary education (ESO) and baccalaureate in an experimental project based on the application of medical technology for the study of Parkinson’s disease (EP).This proposal consists of an information session and two practical sessions to be deve...

This project aims to engage young students of educación secundaria obligatoria (ESO) and bachillerato (last levels of the compulsory high school education system) in an experimental project based on the application of medical technology for the study of Parkinson’s disease (PD). The project consists...

Background: Active smoking and exposure to environmental tobacco smoke may be related to cognitive function decline. We assessed the associations of urinary levels of nicotine and its metabolites with cognitive function. Methods: A total of 553 elder adults at high risk of cognitive impairment and 2...

The article shows the results of a research work aimed at fostering the development of advocacy skills in a group of teachers in initial training of the National Pedagogical University’s Chemistry Licensing Programme, by designing and implementing a learning unit on the implications of food chemistr...

Although the phenomenology of visual hallucinations (VHs) has been investigated, no study to date has related cognitive performance to the content of hallucinations, specifically whether participants who have familiar internally driven hallucinations differ in the executive function from patients wi...

Parkinson’s disease (DP) is a chronic neurodegenerative disease resulting from dysfunctions in basal ganglia, located in the brain, related to motor control. One of the most disabling symptoms of DP is festination, characterised by poverty of movements, short steps, feet on the floor and a decrease...

Although physical activity is generally thought to be beneficial for individuals with Parkinson’s disease (PD), there is limited information regarding current rates of physical activity within this population. In this study, we measured self-reported physical activity levels of individuals with PD a...

Sublethal effect considered as an emerging factor to assess the environmental risk of insecticides, which can impact the insects on both physiology and behavior. Lethal exposure can be causing near immediate mortality. Pests are inevitably exposed to sublethal and lethal dose in the agroecosystem fo...

While the prosthesis is often thought of as a technology or an artefact used to ‘fix’ or make ‘whole’ a disabled body, it has also become an important figuration and metaphor for thinking about disabled embodiment as an emblematic manifestation of bodily difference and mobility. Furthermore, the amb...

In this article, the results of an acoustic study on the production of glides by speakers with Parkinson’s disease and control speakers are presented. Our aim is to explore the dynamics of supralaryngeal joints in MP, especially among non-dysarthric PM speakers. Our results show differences between...

Η Parkinson’s disease (NP) for years was approached by reference to motor-type symptoms. Recent research has shown the correlation of disease with hypoemia and cognitive and psychiatric-type symptoms. In this context, emotional disorders, and in particular the difficulty of recognising the person’s...

Music is currently used for the motor rehabilitation of patients with disabilities due to Parkinson’s disease or age. It also facilitates the restoration of language functions in aphasia. It improves memory in Alzheimer’s disease. Finally, in a context of normality, it facilitates language learning....

The purpose of this thesis is to explore the contribution of frontal lobes and Striatum to the mental representation of familiar activities (scripts), using the models of Shallice (1982) and Grafman (1989). The first study aims to verify the assumption that cognitive patterns would be disturbed as a...

The amyloid precursor protein (APP) is a structurally and functionally conserved transmembrane protein from C. elegans to humans. It has mainly been known and studied for its implication in Alzheimer’s disease (AD) because one of its proteolytic products, the Aβ oligomers, aggregates and forms senil...

Parkinson’s disease (PD) is a neurodegenerative disorder associated with a progressive loss of dopaminergic (DA) neurons in the substantia nigra (SN), leading to a loss of dopamine in the striatum. One of the experimental therapeutic approaches in PD is the graft of DA neurons not in their ontogenic...

Experimental studies carried out by our laboratory show that 17β-E has beneficial effects on MPTP. New oestrogenic compounds such as brain nerve agents are further investigated to prevent or control Parkinson’s disease. This research project examines the effects of 17β-E, PPT and DPN on the expressi...

Parkinson’s disease (PD) is a progressive disorder of the nervous system characterized by the degeneration of dopaminergic neurons found in the substantia nigra. In general, the diagnosis occurs once the patients start experiencing the well-known motor symptoms of this disease, namely stiffness, aki...